Why there are two cyclooxygenase isozymes

Chapter 1 Why Are There Two Sexes ? Turk Rhen and

Why are there deadly drugs?

Some drugs eventually have to be removed from the market because of a negative benefit-to-harm ratio, including an excess of mortality. Drug safety is the result of multiple factors, commencing with how clinical trials are designed, the information generated by and/or hidden through these trials, trial analysis by drug regulatory authorities (DRAs) and the amount of information that DRAs choose...

P30: Are There Anxious Genes?

Anxiety comprises many clinical descriptions and phenotypes. A genetic predisposition to anxiety is undoubted; however, the nature and extent of that contribution is still unclear. Extensive genetic studies of the serotonin (5-hydroxytryptamine, 5-HT) transporter (5-HTT) gene have revealed how variation in gene expression can be correlated with anxiety phenotypes. Complete genome-wide linkage s...

Why Are There Explicit Contracts of Employment?

In this paper we explain the prevalence of explicit contracts of employment, particularly those that embody highrather than low-powered incentives and clauses that supersede the common law defaults. Our analysis is based on an understanding of two fundamental problems that arise when agency relationships are established between a worker and firm. The first is that agency relationships often req...

Why are there different types of synesthete?

For people with synesthesia, sensations in two modalities are experienced when only one is stimulated (e.g., auditory stimuli might trigger colors and sounds). Synesthetes are manifestly different to the general population, but can also be different to each other. First, the condition is widely heterogeneous in that 60–150 different manifestations of synesthesia have been identified (e.g., audi...